Maximize cancer discoveries from FFPE samples with OncoScan Services at IMGM
Dear Madam or Sir,
IMGM’s new OncoScan Service generates high quality genome-wide copy number and genotype data from challenging FFPE samples with enhanced resolution in cancer genes.
Obtaining genome-wide copy number and loss-of-heterozygosity (LOH) profiles from FFPE tumor samples is a significant challenge due to the difficulty of working with limited amounts of DNA that is additionally highly degraded. A simple whole-genome scanning approach as OncoScan Assay avoids the traditional single locus, low-resolution bottleneck of FISH and PCR. Although next-generation sequencing technologies have shown utility in mutation discovery, the requirement for target enrichment and high-depth coverage in order to obtain copy number information from heterogeneous FFPE samples remains a significant challenge.
IMGM implemented now the OncoScan FFPE Assay Kit from Affymetrix, based on Molecular Inversion Probe (MIP) technology. This application offers genome-wide copy number and LOH detection, enhanced resolution in >900 cancer genes and the status of frequently tested somatic mutations, all from a single assay. All these data can be generated from only 80 ng of FFPE-derived DNA within 48 hours.
Experience the convenience of the new IMGM service: just send in your DNA to our OncoScan FFPE Services and let us visualize the results.
IMGM Laboratories GmbH has a great experience of processing highly degraded FFPE samples and our lab has the quality systems in place to handle your project with the highest standard of care and excellence. Take advantage of our expertise and receive data of the highest quality with the IMGM OncoScan FFPE Service.
Unveiling the copy number variations in your FFPE samples would be intriguing but always seemed miles away? Take the first step and get in touch with our team via our contact sheet or call +49.89.4524667.0. For more information on IMGM’s service portfolio check out our homepage www.IMGM.com
The IMGM Team
4th Joint Conference of DGHM and VAAM Dresden, Germany