Follow your nucleic acid therapeutic with IMGM's qPCR Biodistribution Services

Simply use our contact form to get in touch with us!

Salutation*
Title
First name / Name*
Institution / Company
Position / Department
Street
ZIP (PLZ) / City
Country
Intl. phone number*
E-mail*
Area of interest
Subscribe to our Newsletter
Metagenomics
Biomarker Discovery
Pharmacogenetics
Biodistribution
Other
Message / Request

Alternatively, let us know how we can assist you via, email, phone or letter:

IMGM Laboratories GmbH
Bunsenstr. 7a
82152 Martinsried
Germany
  Tel: +49 89 4524 667-0
Fax: +49 89 4524 667-410
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Or visit us personally!

Travel directions

IMGM is located at Germany’s most important biotechnology location Martinsried/Munich.

From Munich Airport by public transport (takes about 75 minutes)

  • take S1 direction "Ostbahnhof", exit at "Laim"
  • change to S6 direction "Starnberg” or “Tutzing", exit at "Planegg"
  • change to bus 266, direction “Klinikum Großhadern”, exit at “Kopernikusweg”
  • walk straight back in the opposite direction of the bus into “Bunsenstraße” (ca. 180 m)
  • cross the turning area, go on straight to the end, turn left (ca. 130 m)
  • You are in front of the main entrance of Bunsenstraße 7a.

For alternative and detailed planning, click the icon below to use the public transport provider's journey planner

MVV - Public Transport to IMGM

From Munich Airport by car it takes about 40 minutes, a taxi costs about 90 €.

Hotel recommendations:

Reference List

IMGM Laboratories GmbH is proud to serve customers in approximately 34 countries world-wide.

 

Name Company / Institute
Dr. Pawel Karpinski Wroclaw Medical University
Dr. Nadejda Valtcheva University Hospital Zurich, Switzerland
PD Dr. Arthur Schüßler University of Munich, Germany
Dr. Hella Kohlhof 4SC AG, Martinsried, Germany
Dr. Spela Baebler National Institute of Biology, Slowenia
Dr. Charlotte Boucher University of the Free State, South Africa
Dr. Leho Tedersoo University of Tartu, Estonia
Dr. Alexandra Gruss INRA, Emergence and Risk (Micalis), France
Dr. Cornelia Grosse Martin-Luther University Halle-Wittenberg, Germany
Julia Vogt University Ulm, Germany
Jürgen Friedrichs Siemens Healthcare Diagnostics, USA
Anders Lonneborg DiaGenic ASA, Oslo, Norway
Prof. Dr. Michael Abend Bundeswehr Institute of Radiology, Munich, Germany
Dr. Ansgar Brüning University Hospital Munich (LMU), Germany
Dr. Stephan Brand University Hospital Munich (LMU), Germany

qPCR - Quantitative Polymerase Chain Reaction

At IMGM, we offer qPCR analysis on the Life Technologies ViiA7 Real-Time PCR System using TaqMan or SYBR Green chemistry.  We work with 96- as well as 384-well blocks and use either general or pre-spotted microfluidic plates in different formats. Thereby, we are able to provide you with ideal solutions from small- to large-scale projects.

The IMGM team can help you with designing your qPCR project perfectly. We generate first-class data and offer bioinformatics data analysis to provide you with high-value information about your samples.

IMGM Laboratories GmbH holds a certificate of Good Laboratory Practice (GLP) compliance for quantitative nucleic acid sequence detection issued by the Bavarian Health and Food Safety Authority.

IMGM Laboratories GmbH also holds an accreditation for gene expression analysis using real-time PCR according to DIN EN ISO / IEC 17025 awarded by the DAkkS (Deutsche Akkreditierungsstelle GmbH).

The portfolio of qPCR services at IMGM include:

  • Assay design and validation
  • Gene/miRNA expression analysis
  • Absolute quantification e.g. for biodistribution studies
  • SNP genotyping
  • CNV analysis

In addition, we offer custom solutions where we use our expertise to counsel you about the optimal approach for your research focus.

ddPCR – Bio-Rad QX200 Droplet Digital PCR

In IMGM’s digital PCR workflow, the reaction is partitioned in approximately 20’000 separate droplets. Thereby, each droplet contains exactly one (positive droplets) or no (negative droplets) target sequence copy. These molecules are then amplified up to 1 million-fold by TaqMan PCR generating fluorescence signals in the positive droplets only.

These signals are used to determine the ratio of positive and negative droplets, which allows calculating back to the absolute DNA amount in the initial sample. No reference sample or standard curve is required for absolute quantification of the target DNA.

Resulting digital PCR applications with increased accuracy compared to conventional PCR are e.g. detection of single nucleotide mutations, rare alleles or copy number variation as well as absolute quantification of DNA or gene expression. Convenient analysis is made possible by a huge number of predesigned PrimePCR ddPCR Assays available from Bio-Rad for common targets. Even difficult samples like cell free DNA or FFPE material are accessible as the droplet approach reduces inhibitory effects.

If you have a question about our qPCR or ddPCR services or would like to request a quote for a specific project, our expert team will be pleased to get in touch with you. Contact us.

 

Go for enhanced analytical power!
Entrust IMGM with your next qPCR project.

Meet us at events

You can meet members of the IMGM team at the following upcoming events:

If you want to be informed about future events, please register for our newsletter.

Microarrays

Microarrays are used to quantify the abundance of target nucleic acids or to obtain genotype information in a sample by sequence-dependent hybridization to DNA probes bound to the array surface. Due to automation and small scale format, thousands of experiments can be performed in parallel on one microarray. This allows e.g. for detecting differential gene or miRNA expression levels within a complete transcriptome or for identifying copy number, SNP and methylation variations within a given genome. At IMGM, we work with the state-of-the-art Agilent, Affymetrix adn Illumina platforms. 

The IMGM team will assist you in the design of a perfect microarray project. We generate high quality data and offer bioinformatic data analysis tailored to your needs in order to deliver meaningful information about your samples. 

IMGM Laboratories GmbH holds an accreditation for gene expression analysis, microRNA profiling, SNP and indel genotyping using microarray technologies according to DIN EN ISO / IEC 17025 awarded by the DAkkS (Deutsche Akkreditierungsstelle GmbH). IMGM has been appointed “Certified Service Provider (CSP) for Gene Expression Microarrays” by Agilent and Affymetrix, as well as "CSP for DMET Plus genotyping analysis".

The broad spectrum of microarray services at IMGM include:

  • Whole genome expression analysis
  • miRNA expression analysis
  • Methylation analysis
  • Copy number variation analysis
  • SNP genotyping
  • DMET Plus genotyping
  • Custom design

♦ compatible with FFPE material

In addition, we apply our flexibility and long-standing expertise to offer solutions tailored to your exact requirements and the focus of your project.

Overview of our microarray portfolio

Application ↓/ Platform →Agilent SurePrint MicroarraysAffymetrix MicroarraysIllumina BeadChips
Gene expression + +  
miRNA expression + +  
CNV analysis + + +
Methylation analysis +   +
Genome-wide genotyping   + +
Pharmacogenetic (ADME) genotyping   + +
CNV analysis in oncology (FFPE-compatible)   +  

 

If you have a question about our microarray services or would like to request a quote for a specific project, our expert team will be pleased to get in touch with you. Contact us.

 

Go for enhanced analytical power!
Entrust IMGM with your next Microarray project.